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Reading Primary Literature, A Practical Guide to Evaluating Research Articles in Biology PDF

pages49 Pages
release year2007
file size7.971 MB
languageEnglish

Preview Reading Primary Literature, A Practical Guide to Evaluating Research Articles in Biology

ReadPirnigm Lairtye rature AP arctciaGlu itdoEe v aluRaetsienAagrr tcliheic snB iology ChristMo.Gp ihlelre n KenyCoonl lege PEARSON BPnj1a1i1 1 1 1 . (l llll ll l lll gs SaFnr anciBsocsot onw ork CapTeo wnH onKgo ngL ondona drid ·j O ity MontrMeuanli cPha riisn gapoyrd ny okoy Toroo nt r:l aAi]recx ander n, irt :u san· lWoiwn irtM : red rsa ndin kt iMnagn arLg:a uHraernp boroagha n upr viSshoarn:Tn oozni er n mn t,m posiatniIdoJ nl,u stBrlaaDtcoikto nGsr:o up turMiann raS:gt aWceeiyn bre rge in B:i ka DG rto up in : vn tnet Sht reeta nSMdta urdiPileoyrsnr y t odv rP rinCtoeurrW:ie te forr, d rP ht oR:i chMaergdn a/FunPdhaomteongtraalp hs R :S hinvtAahnia nDdraenUx neilv eCrhsriityBs,rt oiunUsens iarvrseofdiLa t Vyrne e LeI iB rwonG ourcC hoellMeigcehB,au erla tSopvriAircnbhgUo nri v,eC rytsnhiCityooa�Ti Garr;:;n tatU nirsvi Mtya,r Cyzae Lcohu rCdoelslD eagveDi,ad l IenkdeiU annisavi eDtraayMn, . 14 StaUtn ivtye,Mr iskGiee uBsozw lGirnegSe tnaU tnei veKrastMih.tyGy ,i lKlneeynnCo ogllee, RobGerrte sgoeLnry oCno llMeagrHeke, n Usn iveorNfso irCtyta hr oaltGir neabe onDrsoer,bah o HettiTnexgaLesur t hUenriavne Crisnidtyy, KJlaemMveaisdc ikUsinosin v eTrosKdiodtys ,t man UniveorfWiss ict)o n-Ossihnk JoasLnhei,w SiUsN GYe neJsaecoMk,ii lel eSrt aUOtnheii voe rsit}� BrSatidUt nhi verCsoiltyo -rDoaefdn ovL eor,u Wiosoet Gteoonr CgoiuaUrnnt ei rvsJietyn,n y DellaGpeioertCgroiouaU rnnt i ve(sr tsuidtyCe hnrtJi)os,htG neyo rCgoiuaUrnnte i rvs(sittyude nt) Copyri2g00h7Pt e©a rEsdounc aItnipcou.nb,,l iassPh eianrBgse onnjC aummimni1 n3g0s1, Saonm Set S.a,Fn r ancCiA9s 4c1oA1,l1r l.i ghtsM arneusfearicvtnteh uder. e SUdtn aoitefts e d AmerTihcpiaus.b liicpsar toitobenyCc otpeydra nipdge hrtm isshsobiueool nbd t afriothnmee d publpirisothraoe n rpy r ohirbeiptreodds utcotirianaro genet, r siyesvtoatrel rm a,n simanniy s sion forombr ya nmye aenlse,c tmreocnhiapcnh,io ctaolc,ro epcyoirondlrg ii,kn e.egT w,ooi bstain permiiosnst(uoss m)ea tefrroimta hwlio sr k, plaew arsiert etsqetuunPobe e mssaritoEt dnuc a �on. InPcre.m,ii osDnsesp maern1tt9,0E 0.L akAev eG.l,e nvILi6 e0w0F,2o 5ir.n m foarotrnieardin gg permissciao(ln8ls44 ,78 )6 -2635. Manyo ft hdees niagtuisobenydsma nfaucutrearnssd e ltldoei rssut iithsnehgpi orrudct ares! � ·. tr� mark.Whs eret heod sesaitgianopnpsie ntah rbi osoa knt,dh p eui bslrhw eaawsare oaf clathiedme ,s itginohanabsve epe rni inintn eidct aiopaarsll c la. p s ISB3N9:-7 I8 -08053-4599-5 ISBN0--1800:5 3-4599-X 171 61 5t 4 161 71 819 -CRW-coftl www.aw�bC· Contents Sect1iI:on nt rodtuotc hBt oiooknJ ct 1 WhaAtr Per imRwe)s>e Aarrtcihrc Jl es WhyR eatdhP er imLairtye ra2ture? Howt oU s1 T hBioso kl2et �ct2i:Fo inn dRiensge Aarrtcihc les Window-ShBoorpwpsiinngg: J3ournals NeedilnaHe a ystSaecakrc:hD iantga ba5ses SectiEoxne rc2i 6ses Sect3i:To hnAe n atoomfaPy a per 7 FormaMtattitneg7r s Citat8i on AuthToerhR se:s eaTrecahm9 PublicDaattiPeeosenR:r e vi1e0w Abstr1a2c t Acknowled1g3m ents Referenc1e3s TehE xtenRdeesde aTrecahm1 4 Sect3iE oxne rc1i4s es Sect4i:To hnIe n troduction UndersttahJnead rign1og5n ObservEaxtpiloannsExpa,et riionmntess1, 7 ScieansacC ey clPiorccaels1 s9 Sect4iE oxne rcises 20 Sect5i:To hnMe a terainMadel tsh ods PrelimWionraaknrA dyp prov1a ls Nutasn/ dJ olt'sr:i m1hle/ n 1ptri l_ J J �enp1d 1V 1 ariable� Indepewni d1 eh·'nlt Controalrl1ieI/ \d ConItsli2 I G p LJI TAERRYA TiUiRiE /frproducmiu/llJf ir/pietavt2 a4h ility Th/eJ Piigc thu:r\eJ:J eDreisn1i 1214e nta/ ,.: Corrd1eoS tthudli'easta:11 e1Cdro n1ne1(sn' s/2 i5o Corlrac't·•S,h tu1s:dC ihatlelwns'm u//, iimoisnt 25at CautshaS't<1'u /lJi1<e,11't1'G<H ,ro\u'1/:,J sri w 2i6w (' 01'1S<.t'wu ldlNiieelpsN:1M _etaesudIJr eef.{n.s \ 2i(j Modl�e \�vs2t6ems l!.:vafh{wttpienrRDi emsein2Rt7na / 'ec5t/ i!.,or�ncr ies es 28 ect6iT:oh nRe e sults 29 DealwiinVtgah r iaSbtialtiity2s:9t ics DescrSitpattiivCseet nitTcresan:ld aennVdca yr liiaty3b 0i InferSetnattiiaslta iS casm:pt loaFPe ro opmun l a3t1io StatiTsetsNitucsala:nll Ad l terHnyaptoitvhe3e 2ses PosiRteisvue3l 3t s NegaRteisvue3l 3t s BioloRgeilceavla3 n4c e VisualRiezsiuTnlagtb sal:neG dsr ap3h4s Grap3h5s EvaluDaatti3an6 g Sect6Ei xoenrc i3s7e s Sect7iT:oh Dnei sciuosn 3 InterpreFtiantdiMioennag:n i3n8g ConnecRteiloantsit:ooO n tshWoherirkp 3 9 ExplanaantIdim opnlsi c4a0tions Sect7Ei xoenr c4i0ses Sect8i:Po unt tIiAtnI gJo gether J Reusn s;fo rS t�undat nsJd -. dourcsat Wt,fHite,\ 42 Books� 1t iJc h/o Ru,tJ, i,aPu u pn, L�almRepe uwh It Ii• , � DJG PRI1 RY I 'II LRkI R Secnt1 i:Io ntrodutcott hiBeoo noe ktl mP·igr mp. aa rrpy·eeo srpeseaaa ndr rsot.c oi ahrcr am.wlent aee toyxsh c weeo rlrelolsefsdon c futiiofirs ercctrn eunets dtrs fe ce.boA 1ah '01 o y gsoRyb uee. ga m.d - ar�ded um asg tae r sh1tee·c 1s y1·c,fio1e wuc�nei tbtl1elhc T ohhdape.lu lrtepotono hftgsi hceebnird oksi o tkiailtscpeog apyti ulldo elyyuk y oornt,uw 1eh d g gr eho,u th�p1 rocIetds ess.c ntbhteeos o alnssd t ratyeoguni'eelestld o b egrienang d i articles. WHATA REP RIMARREYS EARACRHT ICLES? Primarreys eaarrtcihac llcseaosl ,rl eesde paarpcehor rps r imlairtye rature, arteho effi cidaolc umtehnsatctsi eunstteico s otmsm unicraetseet aetorah ccehhi r oth.Re erseapracphed ress corriibgefii nndailin ngcsl,u mdeitnhgog dyao nldo resuIlnct osn.td roacsutm,te hnsatytsn thseusmimzaeor,rei vzael,u atlei tp­rimary erataurtree er mseedc onsdoaurryCc oemsm.so enc onsdoaurriycn ecslm uadgea ­ znea rtidcilcetsi,ot neaxrtibaeonsowd,ke sb,sM iatgeasz.wi rnieftsto ergn nt ­he i e erpaulb lsiucca,hsD iscoavnSedcr i enAtmiefiricpc uabnlo,in slshye condary artiScolmepesu .b licsautcaihsot nhsesc ,i ejnotuirnfiSaccl ise anncNdea ture. pubslha m ixtoufpr rei mraersye paarpceahrn ssde conrdeaproPyrr timsary. i papaerraesl wawyrsi tbtyse cni enwthiissletecs o,nr deaprmoyar byte ws r ibtyt en scisetnjsto,u rnoarlo itshteIsrnp,s r .a cytoiucn'eel,elt d ol ooakte acsho urce i caretfoud leltye rimifiit ns pe r imoarsr eyc onPdrairmysoa.ur ryic necsel au d detadielspectdri ooftn hm ee thaondrdse suTlhteasyrt. eh fi er rsetp oofor rtiin alg i resefianrdcihan ngadsr w er itbtyte hsnec iewnhtopi esrtfsdo t rhwmeoe rTkhi.s boofko cuosnpe rsi mraersye aarrtcihc les. . Youe' pvrobasbpleyhn otu rresna dgsi cietnecxeotk .b T ohY dsecn.eb accteespdc iefancttiasfinc cdo ncaenptdths ae,ry we r ittotweanar t due'ndta udi­ encIenc. o nttr,re asseaarrtciahcd lderaser seosafe s m erkgnionledwgg oerc on­tro verasnytd,h eayrw er itwtietpnhr ofesssicoineaanlstt ihins ttesn aduedndi cee. Resehaa rrtcircelpersse sceineitnnp c reoss cw,eh itlete b odoekssbec �hre oiut­ comoeft hparto cReesasd.ri ensge aarrtcirhce lqeudsiiff reersse tn�rgt1a estt� an readtienxgt baonoydko swu,i e lnlc ounnetcweh ra llase ynogbueeg smr edaing theTmh.ib so okwliegltil yv oetu h teo otloose v rcotmhceeh eanlgsl.e PRIMALRIYT ERATlU RE READING WHYRE ADTHE PRIMARYL ITERT.CARE? Do m·sg ·c i1·esa np cwoeerfu l\ Vtaloye arni ffit. ., .r rat-O.....I ...Y.... . .., � . ., ta··tr 1e ct·· 1·s1t am ·s pcsn ta ·cohrt cw1 mabeyeegt ype n be .o r c frmmo_onei�ll rok O\ leYe eyd.xl .pethil. re _ u -_ eann� n_de_ rtm. np ·eh nei .· -eal .•...r,,._ _ rearshcea.i uC.....1e s1· a sc enlat critatoiyfp\ rtiac mg1 en-.tThink 1 ofr esearc aasd o o....t�rw m·a..0l y t.' h s ecn it.ei \fiVcoTh relvpd "'r. ne tht e ban. et .ao p ·pmat le aril yo,vu e1e amdet ohurgreh.a C:d.inot exkst, ab nooIdti e mtnolg e urec .tThe ·c allhenge eyxotauotm fo hpryial onleoukoswwr n in gst chs1 cwei.nane thtsti.n.emA s t )gntti dasefieth yecr n eo uhr _a·b goet e mco .sThn an..et _ 1-anah -zee neswc ieindteiafisc. Trtyoa pparcrohe adriensgea arrtciahcsa lc eh alelr eaenr �g anac o re. Whitlhpeemr airlyi tuermreaa aytp pderyau.rn dtheesr� ace ·ouill fi nddram a ancdo nvterrRoseysr.hec s aciecnotnisstftaasnmc �t et ! ·e nbeecas e t hv.:eo r at theed goefo uknro wleSdogr ee.s eartaircsclc hae nbe ·d eett eecin oe .in whiscchi ecnatriesgftaustlt hlhecyerl uaenesdy icdeen needteood ·e cinteifi probFluemrstl.hi eakgr eo, o dde tencotvithevelec o eo fc iceeonft ehasn enterttwaiiasnntsidsun rgp Friinsaetlshrl.eey s�e archr e·fl eupotcne rea ture scietnhteivmsestIsesdt.l o cumentthset iohropo lriwso .r iatnpidrae cst.ci hcanegse ovteiram nehd o twh ceoyo paenrcdao tmep �ei tteeha cohth eRre.c ogniztheepe r­ sonsaioldfs e c ieinwtci aeld;lud s ecfuoln tteotx hrteee aracrt icolure e ad. Learningt ore raeds eaarrtcihhca olsbe vsi boeunsei fifot usp ltapon uea resecaarricebnhei ro lBoutgthyb e.r ieexfp otstou hrpeeri ma·rtye raffaoturer ded byt hbioso kwlibelebtl e nefiecvieiyanfol n ue· earg arienaa p drim aryl itee ra artAisac lceh.i ludpt, h teIr utmaopnloedekt arn etdpo l ,ta hSetar ar The.m.e loeundo utgodh r iovuIerr iSsehtu tnedrte hrke i tctahbee .Hn o 'e veInr ve er became esskpielaclniIedca d al,tnpl lya any o tteo dYaeymt. b attilththe e trumcpoenttt ieonn uriemc yha dullibtfy ee n hanmcyai pnpgr teicaoinnuad dn er­ stdiannogfm usIintc h.se a mwea yl,e arningt o rperimaraydl ittuerorepea nth e dootro wacrodmsp rehaenneddav ilnugaa tliln gos foc rtsi iefincit normf tin . �am rteora eds he aarrtcaincydlo ewusi b lelc ommeo rcaeo ndnfieatdn e ffiti e - Judogfsec ieinntfiofirmc,a tai ornemseafrsukklaii blntllo ya d fu ord . HOWT OU STEH IBSO OKLET tbaL.oi c�e xaWpt�.nni.sia gdtt vud oh.r·itavao et fr nidpaioycP rvmd1eem ·ea iiary e sun, n ,ec t a r yx·rmem·geFp agert sowtt r ie·rlhocca y ·gla ahrto er tt ifiuxee cchsib'aae hl sae msta el ue ilhsysonthlnyaeo t ieg n ue lk daart efieey oBah nd.ocumtiog iloil i rn od betnlteru ha brcdnd·aro maeda· an nt sala di0 c° mk nnl eeeg w.o tn� 'a eky oau o mcpeetnatn grYl.oe 1un1'e etdoo os tabnytde h atrean dp rac- at.rtib1e 1ca .scebi , oat iht. mnoh g' osc ktantm· rasg una phcd nrt ,ea.ai c noaltdrani enec deeaefiidd hsn.0. gS o i its ithr aei.dn grese arch Thibso okiltse�h it n strmuacntuyiaoolunn ' eletldoq uicbkelcyoa mt ea lented reaodfre� ree aracrht iTchlseee sc.tc ioovnhesor wt ofi nadr titchslete rsu,oc fture reseaarrtcihc ltehfseo, um raa inpnda rotfas na rtitchIlene t:cr toidMouant,e rials an,dM ethoRdess,u alntdDs� s,c ussIinao dnd.i ttois otnu dtyhibinosgo klet, yo1u�a ls�eoe tdo s truwgigtrlhee s eaarrtcihyc oluersTs heeeln fd.- eocft-ison exercwiislpe·lrs o mt,ph. tpa tr actt.ih ceaeys;y ko tuo c riltyir ecaaapdl a rpb ey ap1yp m g·te hs ec.ts 1 dv0a �1ne D.e �pndm?gyn �u rc �orsaen idn sotrry,uom cuit ght c�hoe y ouorw na rtuiscmltgehm es tructsieocnt2osi ry o omnu i rn scttrmouirg ht assoingen. Asy obue gyionu jro urnienytt ohp er imlairtye roafbt iuoyrl,teo h gewriel l inebvlibyteo a bstaacnfldre uss trBauItth i oopyneos u. awlifislnolsd a taicstifinon overcgot mhciehn allaennpdga erst iciintp haet ipnorgfso ccieees.ns c Secti2o:Fn i ndRiensge Aarrtcihc les Thmea jjooru rnianbli so medniocpwiu nbelo inslihMn eo.rt eh aam ni llsciioiencfin t articlaerasev aifrleaoebn lt ehI en tearnnemdta ,nm yo rcea bnea ccefosrsa fe eed. Alownigtthi hsa vailcaobmicelhsia tlyl Secnigeennste.ie tsdofit nsrd e leivnan­fto r matiaomni adm sotu ntoainfd aatnatd h iennt ellaingaeltnyhtzele y i nformation. This sectdieosnc ritbhfireess st t elpo:c aatniadnc gc esrseinsgea arrtcihTc hldeee stail.s wiblels pectioyfi ocui rn stiatnusdtu ibodni sscoiw pewl iiflnolec ,ou ngs e neral strateangdfri eeoesnli ndea tabYaossueh soa.ul llsdeo arn a botuhstep ecrieofisucr ces availaobnly eo ucra mpus. Thset ratyeogui eesm pldoeyp eonwntdi h lel puorfyp oousre sAeryaeor uc h. trytiodn egv eltooppf ioaacr researSccha npntaihptneeag rbo ?lfc e o ntoefan ts prestjioguirnomauilsg ghitvy eo suo me idecausrr ehanobrttoe uste aareras.c h You might atas lescoo nsdloaouroryskc u ecashst extbaonomdka sg azinfoer ideas. If ysoeul'evcet eadl rae aagrdeeybna ue,ntr e aetldofi ntartidoc pliec witthhitanot p tihcey,no mui gdhetc itods ee adractha boafrs eesse artia rlce.h Orp erhaps yofuo'uvanenid n atlerreaearsdttyii cnnlgoe nw e aetndord e aodm e relaatretdit copl uetsi nci otn tIentx hti.s ycoamusi egl,ho toa ktt he e it citaenasdl sseoa dractha bases. WINDWO-SHOPPBIRNOGW:S IJNOGU RNALS Suppyooswuei sthob rowjsoeu rntaodl esv etlp oiip d a . rhea ny uofi nd journaOlnsep? l aicyseo usrc holoilb'rwsah rhiy ,hh a.r dp ioef m anjoyu r­ nalHsa.v itnhpgea pjeoru rnianyl o uhra ndasnb parutliau re lfywu hle yno u arber owsfioinrng et setrtionpgiO cfos u.r ,ms a njyo urnaarlae lo a vaielabl onliIynfeo a.ul rekandowywh ijcohu rnyaowlua nttob roewa, impslter aitsegy tol ociattse howmietpahanI g net e,rne eatre cnhg iOnnel.ij noeu rnhaalvse straighitnftoerrtwfhaaaarcltdel y ouowt ob rowosree a rfcoahrr ticles. READIPNRGI MARLYI TERATEU 3R orAgnahoentr twih aze.Ftyemo oas �crxc a emspos1 e nI .myo e u Jw ·miofialunllimds tsa h nriyoma uprw gotehaJb. enos ttuiah rntlcamsat bl ..1t 0om s agae dnid- c.m ea tteh H .ih wgter pres,s s ei thoesdt byS tand.f oUrni.v Leirraribs.eis t y (ww.w.h 1.ge .howrtEgxrce)l.ln eti nrsutcntsfi oor. tuhssemi gat reae av illeaon bi st hamonbedrp oaYiwtgo shetucee. a1ae s ne0ef o 1i.acntes o t n sfJo·ot u rfnrae len'cscti h seossoouF.sneo mterah mnaJ.ayto t uclrnyhsaaoer,cueis csne tostrst ht ees maobsoratuye atecra e pfne�tu1�tp·i tl1buseld.i y aa c tr cintelo.Asir ueeusfqieusferal as u turboesft c hHrewii igptfrhthewsi aeiioci retncasese,la s aivn iasbgolltf ei J.uO m awlistfr hee o nle aicncess. . . Amlos1t00 0 s ·c t1Ie' Jnfio. cu mlaasr heo tesdo .nH 1ghwr.et H.o wc aynuo d e.dcei wh.i Jcoh.u 1 sma art eeh m osrteev lnatt oy our tWohpiicachrt? eeh m osrte iblael? Wh.i acerht h meot sPr e stoiug?·sO i. ne strat1·.ets gol y ok o1 nt·he r .�e e1necresset·nc rn o f yocu1ar s tesxt obok t osee w hicohu mJaalrcse.i ttehde;as rele i ykt. eo ble r eeavlnt tyoo cuoru e arnshdi grheglayr d·Ae s.d yboeug.t i ofin n .rd e sceharta ircesly,ou c na alcsehoc kt heRierfeen rceCsied t ecstioangsat;ih n.Je, o urnsta hlta� rrege uarlly ceidta er teh mosutesfu la npder stigJioouurnsra.ankil n gas lesxo.i O snetw iedly usmeeda es,tu hriem pafcatcm teoars,uh roewms a ntyi mtehsare t isc ulpbeslhdie inaj ournaarcleeid tb yo ther Fairnt,aiy lcollcuyea sn. ascko uyironstuserrto u rc orl ibrWairedliyaren a.da ncdi tjeodu rtnhaalptsu blriesshe ianrb cihog l)o inclSucdiee:Nn acteu,Cr eel,Dl ev,le opmeGnetn,e tPircosc,ne gesod fit he NatiAocnaadle omfSi ceise( nPcNeAJ So)u,r nBailo loofCg hiecmailJs oturyrna,l ofCl inIincvaels tJioguartonifEao xlnp ,e rimBeinoltAoamgley r,i Jcoaunrno afl PhysiNoeluorgJoyon,u, rn oafBl a tceiroloagnydP, u blic oLfiS bcricaeeryn (PLBoiSo)l Tohgiiyass.p arltiitsahtle;a r rmeea noyt her oujtosuatrnlasn.d ing Anoertu hsewfuebls iitsBe i oMCeedn t(rwaw.lwb iomedccoe)m.nw trhhai l . pubelsmi oserh tha1n5j 0o urnianlcsl,u gdeinnetgri atsllu ecashsB MCB io/oay anJdo uronfBa ilo laongsdyp ecitailtislzueecasdhsB MCP hylsgyoi aondR IC Mirocbiogyl.Ao rteispc ulbliisnh eBdi oMeda roCeep netnr-aamlceani cnecss, thtahtce yab ne fr eelayc ceasnsddei ds trYiobcuuan ts eedah.alr lco ft hBei, ol.de Cenrtajlorn ualorsb r wosep arctuaril tliets. Ymyummtaafihmrolaaoe� a s.Ir cseOStanu,yyua fiemau·aye tw t n c1tuer anrn1.pr ·sIpp1 . bhneuu1lo1sae 1c1 edtd sete pmcc. pli eeac aoicsn yl 1c k a.n i sy . aonia cs rhrtno� u n re etuspt sastthvtc , drtbs u hi.seaee eo 'oaah noin itPpattapa da ti 1 eani rnvee eece trhhimacl v·hr·1e· fub c ehntow nuleuae; gto Js n tt 1 ru sl·ere Ie . tte r y-i sasaoect 1snseurn h n a·npI txedel atuoo t si aa a s m·a.tetvac towtaaemn,.ldlAi,·tf v oth etie ia avsArcg l.l cl .uyahett rninidkl dwuyl bcy sori ot.aldxooo uimg -l ehuosli taog nia tfbnvitaghtet r nahr to tntp et ennP oet ha a betw ha ofrt Duhopr l ifoIaerb RuesFu svrteco'n rcu ttyerlif ]tdeeiic l r1 tod'si aclartoaitaho crn,tearm i ne :tsdfuo-it nreels te.wnfta i t oaelnchs steiid 1 oeuity.f;fcr hmr-lnrla Tr o oota tlb omsoF aate®ty p the eonnhu l\\ f.m1u rf spm h e rtuoaI· teo p a neae trrlht x eprna h tttttomdefeni mttvP nprtmrtstt hrte D p prdaonlrhe v·eec ,ehpF.e dhgtle·iar·rn isrn.r. s es crtib, d PYitn· "'ie in oee oet tsoo l ° 3c rnDlh o fFt ek t·hn ue -ee 4 REANDGIP RIMLAIRRATYTE URE tt<.svI..urt a .�p rst1mfn .��a'1y a mt urip, 0 oah-tsd .1ff.\ a't h rt 1 \ntcrr a .h to he...t amtf t t pmmnehovyu me1ri.r ob.fn l ssuoal ftot irnricyer.a.o ttsaor mr bnbihhnua aoyLy ecele ru.rtr o l od p tiic·eo diTogea pd kaachnsi ta siSetltceu.ni,p.onecr t h h asFn o aigo .hu c .l ·geuetp lrec nm· cxe nra da letk cv ·mt ttsecsn.arlapw n ba � eose· yIb n vn e'i uno be am· u c. d atuxle 1wtau b, ehte hnes d·lch 'ctd.ml hte m nt 1· c te -l 8o ava.i altma. ab nlm s.t 1ntsui,ats n1 o tthoetorhle a nta sby olute 1cto e n tstofyru cs tha1tta p artiacrut.l1 acrl e OLEI NA H AYSTASCEKA:R CHGID NAATBASSE uppoosu h av vedl opreeds etaao rpcaihncn de e dt ofi nrdele vapnrtai rym s.u r . rm ayyb ohua vfeo uans di njgoluera nrate alin cndlee dt ofi nadd Id_ ' ttaol�nt' l}c o nth. e �set opIinbc o.t h sceaasrecash e,seir anrgac rthei dcal-ta ba wibl la ne ffecatpipvreo Saecvhed.ra atla bmaasybe eas v laaieb olny our � pu; hoot hoen bee sstu ittoey do utro pAilct.h odeutgahiw livsla lry h0 htfrl y mo nteo ntehxett hg,ee neprrailn cwiipbllelte hssea em,a nmdo ts databan tahicen l pifnuslt rtuocg teyitoo sunt sa rted. A ane amwpel1'ed1 ,i sctuhfrsees e alvya iPlUaMBbE lDes i,wt hiicpsha rt e fa ni nrtc onnceocltleedoc fdt aitoanbo apseerbsay tt ehde NaCtnitrfoo nra l e e Biocth nolIongfyo rm(aNtCiBwoIwn,w .ncbi.nlPmU.BnMiEahDl. lgoowv ). u tro arcahr tiicnal lems5o ,s0tj0 o0u rinnma eldsi acnirdne el fiaetleIddns . total1 5mo ivlelri ona rciein tcaltGuiidovetnedhsn.he u gneu mrbo fc iitoaintn e PUBMEsDe paruasteiafnrugtl i frcolmae lsol ft he craebnse tt r iGcokody . earcwhi blecl o mprehmeenasntiihvnewegiy, rl elt aulorlrmn o sotfte hart ilec onap artitcoupalinacdr, awlibsleowl e llfomceuasnteihdne,gy turnw ialral­ r e e sonanbulmebo efar r tiwciltfeehwsi rrelaervtainctl es. Thceh oicsee aotrfec rhim ossb viocursultcyoai nae lff ecteiavrYeco huan. finde artcehr omnst hfier psatg oefr eseaarrtcihlc olofekosa r;I t io fnnts beltohwAe b stYroamuci tg.ah ltps iouc pku setfeurlim snse conoduarr ry b browgs ianrticSlcei etnoitftitulsesetnsess p . e ciwaolriwdzi eptdrh ei m _n­ ingssoi t haellstpooks n oswo moeft hsec ievnotciafibcFu olraa rmlyp ..w htle thgee nlep ruabslaiy"csh e art asa ctiteanctksi,as'"yut' d ndm aaryi da �t:� "mycoardiinafla r"chteifaoarnit,l ""u craer,id"si cahc''e mi,rna. t urlifiar b ln­ lat"iw ointe,ha cohft heep hrasesas ohnaw1vht iad nigrffin mt ani.n arg� usidnigff nettr eerwmisrl elt duirffne reetonsfat r 1t. is n. in actwlhh t tertmous s cea bned iffitcodu lrttm i,an n sdo mt rmi arllr mf Y O edd . Donb' atf rtaosi tdart sear athr imtn hgna i thw tbi ithmr tt .a rhc ar'e fre anfda satn,bd c rt ta sr ctrh m s ocf�atnnb la nd fr m th citotinas rt urbnyae ndi nisteiaarlc h. baBss ci eanucsslac unc idto tseinm staryuso sulvebla jreveidotcon c tuna fssb utIrlhnPs a UarBmycMe.oE, t nDp th, eme t anyed ra� met a- caleldt hM ediScuablcj tH adin(gMs H ).Y ouc afinn Mde SH wordYs REAIDNPGR IMARYL IETRATURE S

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