Osteoarthritis is a major public health issue due to its impact in term of handicap. Moreover, Ageing of the world population and outbreak of obesity in industrialized and non-industrialized countries will dramatically increase its incidence in the next years. Regarded as a multi-factorial disease, today mechanistic and inflammatory theories are no more opposed but, on the contrary, are framed within the same continuum: osteoarthritis, inflammation and degeneration. In order to collect major information in a benchmark book on the fundamental aspects of this disease, internationally well-known authors, from multiple specialties, gathered to analyse, dissect and finally try to understand the secrets of a disease which should no more be regarded as the common and relentless result of ageing or of passive wear but much more as an active disease able to benefit from the best targeted pharmacological (anti-cytokines, inhibitors of signalling pathways, inhibitors of proteases, etc.) and non-pharmacological (cellular therapy, gene therapy, cartilage engineering etc.) therapies, current and future.IOS Press is an international science, technical and medical publisher of high-quality books for academics, scientists, and professionals in all fields.     Some of the areas we publish in:    -Biomedicine   -Oncology   -Artificial intelligence   -Databases and information systems   -Maritime engineering   -Nanotechnology   -Geoengineering   -All aspects of physics   -E-governance   -E-commerce   -The knowledge economy   -Urban studies   -Arms control   -Understanding and responding to terrorism   -Medical informatics   -Computer Sciences

OA, Inflammation and Degradation: A Continuum - Volume 70 Biomedical and Health Research PDF

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