High secretion of interferons by human plasmacytoid dendritic cells upon recognition of 1 MERS-CoV 2 3 Vivian A. Scheuplein,a Janna Seifried,a,e,* Anna H. Malczyk,a,f,* Lilija Miller,b Lena Höcker,b 4 Júlia Vergara-Alert,c,h Olga Dolnik,c Florian Zielecki,c Björn Becker,d Ingo Spreitzer,d Renate 5 König,e,f,g Stephan Becker,c,h Zoe Waibler,b,f,# Michael D. Mühlebacha,f,# 6 7 Oncolytic Measles Viruses and Vaccine Vectorsa, Novel Vaccination Strategies and Early 8 Immune Responsesb, Bacterial Safetyd, Host-Pathogen-Interactionse, German Center for Infection 9 Researchf, Paul-Ehrlich-Institut, Langen, Germany; Sanford-Burnham Medical Research 10 Institute, Infectious & Inflammatory Disease Center, La Jolla, USAg; Institut für Virologie, 11 Philipps-Universität Marburg, Marburg, Germanyc; German Centre for Infection Research 12 (DZIF), partner site Giessen-Marburg-Langen, Marburg, Germanyh 13 14 Running title: MERS-CoV interacting with immune cells 15 16 #Address correspondence to 17 Dr. Michael Mühlebach,